RGCC Testing


RGCC (Research Genetics Cancer Center Group) is the name of a cancer research facility founded in 2004 by Dr. Ioannis Papasotitiou. This facility offers cutting-edge ways of detecting early cancers, maximizing effectiveness of therapies, monitoring cancers for progression or occurrence, and enhancing the body’s ability to destroy cancer cells. 

Its state-of-the-art research and development gives patients the ability to detect cancer cells in the circulation (also known as circulating tumor cells or CTCs), even if no solid tumor is yet formed. 

Technology called flow cytometry isolates these CTCs with a 97-99% purity, allowing the cells to undergo further molecular and genetic analysis. These CTCs can be tested for aggressiveness, resistance, and response to therapy. RGCC can also offer extremely helpful testing that predicts the cancer cells’ sensitivity or resistance to various chemotherapies or NATURAL substances. This helps take the guesswork out of treatment protocols and allows patients and providers to utilize the most effective therapies possible. 

RGCC also offers treatments that help the body fight and destroy cancer cells without chemotherapy by shutting down cellular replication (SOT) or mounting a specific immune response to the cells (Dendritic Cell Therapy and VAX-Q-RE)

Dr. Wheeler Talks about RGCC Testing

Quick Glossary for RGCC Tests & Treatments

CTCs: Circulating tumor cells found in the bloodstream.

Phenotype markers: Characteristics or observable traits of cancer cells based on their expression of various genes and their resulting protein products. Phenotype markers include traits such as size, shape, behavior, growth patterns, and response to treatments. 

Gene markers: Specific DNA sequence variations associated with cancer cells. DNA markers provide insight into genetic predisposition or alterations driving cancer development, while the phenotype markers (see above) reflect the visible properties and behaviors of cancer cells. 

Stemness: Cellular properties that sustain progression of cancer cells. These include enhanced abilities for self-renewal cloning, growing, metastasizing, travel to distant sites, and proliferating. 

Recurrence: The return or reappearance of cancer after a period of time during which the cancer was believed to be in remission or completely eliminated. 

Resistance: Likelihood of cancer cells to withstand treatments and continue to grow, divide, and spread.

RGCC Test Menu


Basic test used for follow up and monitoring of treatment efficacy. Provides information on number and concentration of CTCs and is helpful for detecting relapse or recurrence. Does not give information on phenotype or stemness of cancer cells. Can be ordered every 3-4 months to monitor progress.

Oncocount Sample Test

Can be used for screening when cancer is suspected but not officially diagnosed. IT can also be used when a cancer is present but the primary source is unknown. It provides information on CTCs, phenotype markers, and stemness. Can be done every 3-4 months during cancer treatments to show if the circulating tumor cell count is going down in response to treatments. It also gives phenotype and stemness markers.

Oncotrace Sample Test

Beneficial as a follow up for any of the following types of already diagnosed cancer: Breast, Prostate, Colon, GI, Lung, Melanoma, and Carcinoma. It detects CTCs, stemness markers, and phenotype markers. These markers are narrowly aimed at the specific cancer being treated and are different from the broader range of markers offered with the Oncotrace panel.

Breast Cancer Sample
Prostate Cancer Sample
Sarcoma Sample
Colon Cancer Sample
Gastrointestinal (GI) Cancer Sample
Lung Cancer Sample
Melanoma Sample

Includes testing for CTCs and sensitivity or resistance to chemotherapies, monoclonal antibodies, molecular therapies, and radiation. It detects the upregulation or over expression of over 70 different tumor-related genes that give information about how the cancer is likely to respond to various treatments. This test does not include sensitivity or resistance to natural substances.

Onconomics Sample Test
Onconomics Extracts

Includes testing for CTCs and sensitivity to ONLY natural substances. It doesn't include tumor-related genes. 50 different substances, along with any 5 of your choice, are tested. Additional natural substances can be included in the test for an extra $50 each.

Onconomics Extracts Sample Test
Onconomics Plus

Includes the information in BOTH the Onconomics and Onconomics Extracts test. The most comprehensive of any test available.

Onconomics Plus Sample Test

How to complete an RGCC TEst

1. Complete an office visit with Dr. Wheeler for a thorough evaluation ($250 for first time visit, $150 for follow up visits). 

  • Here you and she will decide together the best approach and the best tests to run. There will likely be additional tests that would be beneficial (such as an endobiogeny panel). 

2. It is important that all anti-cancer supplements and therapies be stopped two weeks prior to blood draw. If free radicals are being produced or if cancer cells are actively dying there will likely be debris in the bloodstream that can skew the results. Two weeks gives enough time for the body to clear the debris and give the most accurate results possible. Below is a list of necessary wait times for common treatments:

a.) No wait period:

  • Hyperthermia (generalized, such as infrared sauna)
  • Cryoablation
  • Hormone suppression therapy
  • Checkpoint inhibitors
  • Hyperbaric therapy

b.) 14 day waiting period:

  • Vitamin C or ozone (major autohemotherapy or prolozone)
  • Natural cytotoxic substances (oral supplements) including: Agaricus blazei murill, Amygdalin, Artecin, Artesunate, Ascorbic acid, Avemar pulvis, Bio D Mulsion NuMedica Micellized D3, Butyric acid, C-statin, 1Cordyceps sinensis, DCA (dichloroacetate), DDG (dideoxy-D-glucose), Doxycycline, Frankincense, GcMAF, Lycopene, Mito Booster, Mitochondrien formular, Onkobel Pro, Oxaloacetate, Poly-MVA, Polyphenole CA, Ribraxx, Saliciniu, Super Artemisinin, Theaflavin, Ukrain, Vitanox
  • Chemotherapy (platinum derivative)
  • MOAB or SMW (small molecular weight) drugs
  • Radiation
  • Contrast dye
  • Surgery (simple/routine)
  • Fever
  • Immunosuppressants
  • Cellular therapies (VAXO-Q-RE, Vaccine prep, Dendritic cells, DendroCov)
  • Mistletoe

c.) 21 day waiting period:

  • Off-label medications (i.e. Ivermectin, FenBen, itraconazole)
  • Chemotherapy (non-platinum derivative)

d.) 30 day waiting period: 

  • Surgery (major)
  • Hyperthermia (local/concentrated/microwave ablation)

e.) 120 day waiting period:

  • Blood transfusion

f.) Not candidates for RGCC therapies (but able to do testing)

  • Radiation seed implants: due to prolonged and undetermine time of radiation exposure.
  • Gamma Delta T Cell Therapy: due to potential interaction with RGCC therapies

g.) Patients wanting SOT for Lyme/EBV/Viruses ALL antibiotic/antiviral/antiparasitic medications and therapies must be stopped 14 days prior to blood draw. These include IV vitamin C or ozone.

  • Detox supplements such as binders, glutathione, cytokine reducers, etc will not interfere with action of SOT and can continue to be used. 

3. All therapies can be resumed immediately after the blood draw. 

4. Processing time:

  • Oncotrace, oncoblot, xxxxx -- results should be availabe in 2-3 weeks. 
  • SOT Once tests are sent, results are available in 2-3 weeks. 

5.) For patients wanting SOT:

  • Lyme -An additional 4-5 weeks processing
  • Cancer -

Cancellation & Refund Policy

Refund issued at 100%

(but BEFORE patient's blood is drawn) $100 kit fee charged. The rest is refunded. This also counts for remote patients who need it drop shipped.

$100 kit fee + $100 cancellation fee charged. The rest will be refunded

50% cancellation fee charged. 50% refunded

75% cancellation fee, 25% refunded

100% cancellation fee, no refunds.